Liver Transplants Could be ‘Avoidable’

Liver Transplants Could be ‘Avoidable’

Patients who have severely damaged livers might not need a transplant as their own liver is actually re-growing doctors at
a London hospital say.
Patients who have had a liver transplant but have retained portion of their own liver experienced a re-growth and recovery
of their own original liver following the transplant. Of the group of patients studied it was found that the liver
transplant may not have been required in seven out of eleven cases.
There are only a handful of facilities who perform the auxiliary transplants where the damaged liver is left in the body
King’s Hospital in London being one.
The hospital has a leading liver transplant centre and the auxiliary operations are usually performed in expected cases of
liver failure which are caused by viral infections or overdoses rather damage which is sustained over a long period of
time through conditions such as alcoholism.
The operation is used to try and get someone through an illness at its most critical stage.
The doctors looked into the liver cell chemistry in the patients analysing cells from those who recovered and those who
didn’t.
The BBC reported that Dr Varuna Aluvihare had commented:
“There was a big difference right from the point of transplantation in the expression of some very small molecules between
the group that would three years down the line regrow their liver versus the group that didn’t.”
The molecules in the liver controlled the way that the liver cells grew. The Doctor discovered some regeneration in the
cells.
“Some of them were already starting to regenerate. So what we may be able to do is come up with a better set of tests to
allow us to identify those patients who are already regrowing and may not need transplantation”
“So we may be able to remove a group from the transplant list.”
The liver is known for its ability to heal itself and this study has helped doctors understand more about the organ.

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